April 16, 2025
Stroke thrombectomy
Stroke thrombectomy is an interventional radiology procedure used to treat ischemic strokes. Ischaemic strokes were traditionally treated by physicians using systemic medical agents such as anti-platelets (aspirin) or thrombolysis (clot-busting drugs).
A 2020 Cochrane review of 19 studies concluded that “endovascular thrombectomy can increase the chance of survival with a good functional outcome without increasing the risk of intracerebral haemorrhage or death” for large artery occlusion ischaemic strokes in the anterior circulation.

An ischemic stroke occurs when a blood clot blocks an artery in the brain, preventing oxygen and nutrients from reaching the affected area. This can cause damage to the brain tissue and lead to a variety of long-term disabilities or even death.
Along with symptoms of slurred speech, weakness down one side and facial droop a CT scan of the head can help diagnose an ischaemic stroke. Importantly it can exclude a hemorrhagic stroke, when the same symptoms are caused by a bleed on the brain, usually after an aneurysm rupture.
Many UK centres now use artificial intelligence to determine the patient’s Alberta stroke programme early CT score (ASPECTS). This 10-point score helps rapidly triage patients who may be suitable for mechanical thrombectomy. In hospitals without a thrombectomy service this can mean urgent patient transfer to a thrombectomy centre.
Thrombectomy is a minimally invasive procedure that can quickly and effectively remove blood clots from blocked arteries, restoring blood flow and reducing the risk of long-term damage.
The procedure is typically performed by an interventional neuroradiologist and involves the use of a thin, flexible tube called a catheter. The catheter is inserted into an artery, usually through the groin, and guided to the site of the clot in the brain. Once in place, a specialised device (much like a hoover) is used to remove the clot from the vessel, allowing blood flow to be restored to the affected area of the brain.

Thrombectomy is most effective when performed within the first few hours after the onset of symptoms. Time is brain. It is often used in combination with other treatments such as thrombolysis (clot-busting drugs) to achieve the best possible outcome.
Thrombectomy is a safe and effective procedure with a high success rate in treating ischemic stroke. It is associated with lower rates of disability and mortality compared to other treatment options, and offers patients a quicker recovery time with fewer complications. However, it is important to note that not all patients are good candidates for thrombectomy, and the decision to undergo the procedure should be made in consultation with the patient or next of kin.
Bites:
Stroke thrombectomy is a powerful tool for treating ischemic strokes, offering a minimally invasive and effective way to quickly remove blood clots from blocked blood vessels in the brain.
Thrombectomy is an effective and safe procedure performed by INRs to reduce disability and mortality associated with ischaemic stroke.
It is most effective when the clot is retrieved soon after symptom onset. ASPECT score helps identify suitable candidates.
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